منابع مشابه
Distinction between Pore Assembly by Staphylococcal α-Toxin versus Leukotoxins
The staphylococcal bipartite leukotoxins and the homoheptameric alpha-toxin belong to the same family of beta-barrel pore-forming toxins despite slight differences. In the alpha-toxin pore, the N-terminal extremity of each protomer interacts as a deployed latch with two consecutive protomers in the vicinity of the pore lumen. N-terminal extremities of leukotoxins as seen in their three-dimensio...
متن کاملRole of phospholipid scramblase 1 in type I interferon-induced protection from staphylococcal α-toxin
446 Virulence Volume 3 Issue 5 Recent studies have identified cytoskeletal elements in bacteria which play important roles in cellular morphology, cell division, DNA segregation and the establishment of cell polarity. However, our understanding of the contribution the bacterial cytoskeleton makes toward virulence is lacking. The MreB protein is a bacterial homolog of eukaryotic actin and intera...
متن کاملStaphylococcal enterotoxin B and α‑toxin induce the apoptosis of ECV304 cells via similar mechanisms.
Staphylococcal enterotoxin B (SEB) and α‑toxin produced by Staphylococcus aureus (S. aureus) are important in the pathogenesis of diseases. In the present study, we investigated the effects of SEB and α‑toxin on ECV304 cells. It was identified that both SEB and α‑toxin were capable of inducing the apoptosis of ECV304 cells in a dose‑ and time‑dependent manner. In addition, SEB and α‑toxin were ...
متن کاملMitogenic activity of staphylococcal exfoliative toxin.
Exfoliative toxin from Staphylococcus aureus was mitogenic for murine spleen cells. It was primarily active on T lymphocytes but also significantly stimulated B cells from the spleens of nude mice. The mitogenicity was not affected by simple sugar or alpha-methylpyranosides. N-acetylglucosamine and N-acetylgalactosamine inhibited its effect. Exfoliatin was as powerful a mitogen as the enterotox...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1967
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.94.4.1170-1177.1967